Description:
JK-184 is a potent downstream hedgehog (Hh) signaling antagonist that functions by alcohol dehydrogenase 7 (Adh7) inhibition, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). Hedgehog signaling plays a key role in a wide variety of developmental processes as well as cancer progression. JK-184 exhibits antiproliferative activity.
- Molecular Weight: 350.44
- Molecular Formula: C19H18N4OS
Purity: 98%
- Appearance: Light pink color
- Application: Differentiation
Synonyms:
JK184; JK 184
More details are to be found on supplier website
